Eckardt V F, Adami B
Klin Wochenschr. 1980 Mar 17;58(6):293-7. doi: 10.1007/BF01476571.
Esophageal electrical potential difference (PD) was studied in 9 patients with symptomatic gastroesophageal reflux and in 9 healthy control subjects. None of the patients revealed gross mucosal damage by radiography or endoscopy, but all of them showed positive acid perfusion studies. In the stomach and across the lower esophageal sphincter PD profiles were remarkably similar in patients and controls. Throughout the lower esophagus however, PD values were slightly higher in patients with symptomatic reflux than in healthy volunteers. These data are in contrast to a previous investigation, in which patients with reflux-induced gross mucosal damage revealed a decreased PD in the lower esophagus. Thus it is concluded that PD measurements of the lower esophagus do not appear to be a valuable test in the differentiation of chest pain of cardiac and esophageal origin.
对9例有症状的胃食管反流患者和9名健康对照者进行了食管电位差（PD）研究。所有患者经放射学或内镜检查均未发现明显的黏膜损伤，但所有患者的酸灌注试验均呈阳性。患者和对照者的胃内及经下食管括约肌的PD曲线非常相似。然而，在整个下段食管，有症状反流患者的PD值略高于健康志愿者。这些数据与之前的一项研究结果相反，在之前的研究中，反流引起明显黏膜损伤的患者下段食管PD降低。因此得出结论，下段食管PD测量似乎不是区分心脏源性和食管源性胸痛的有价值的检查。
