Chu T M, Holyoke E D, Douglass H O
J Surg Oncol. 1980;13(3):207-14. doi: 10.1002/jso.2930130304.
Data are presented suggesting the presence of pancreas tumor-associated antigens. Slow progress has been made during the past few years in the identification of pancreatic tumor antigens that may be of clinical usefulness and it seems unlikely that many of the practical problems now being faced in identification and isolation of these antigens and in development of a specific, sensitive assay will be solved by conventional immunochemical approaches. The study of antigen and/or antibody purified from immune complexes in the host and the application of leukocyte adherence inhibition techniques to immunodiagnosis of pancreatic cancer are among the new approaches that may provide effective alternatives in the study of pancreatic tumor antigens.
数据表明存在胰腺肿瘤相关抗原。在过去几年中，在鉴定可能具有临床应用价值的胰腺肿瘤抗原方面进展缓慢，而且通过传统免疫化学方法似乎不太可能解决目前在这些抗原的鉴定、分离以及开发特异性、灵敏检测方法过程中所面临的许多实际问题。从宿主免疫复合物中纯化抗原和/或抗体的研究以及白细胞黏附抑制技术在胰腺癌免疫诊断中的应用是新的方法，可能为胰腺肿瘤抗原的研究提供有效的替代方案。
