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搏动血流能否改善低温体外循环期间的灌注?

Does pulsatile flow improve perfusion during hypothermic cardiopulmonary bypass?

作者信息

Singh R K, Barratt-Boyes B G, Harris E A

出版信息

J Thorac Cardiovasc Surg. 1980 Jun;79(6):827-32.

PMID:7374197
Abstract

Each of 10 patients undergoing hypothermic cardiopulmonary bypass was perfused in turn with (1) the standard flow delivered by a roller pump and (2) pulsatile flow induced by a "pulsatile assist device" (Datascope Corp., Paramus, N. J), presented in random order at the same mean flow. Whole-body oxygen consumption, blood lactate concentration, systemic vascular resistance, urinary flow, and thermal gradients were measured during each type of flow and after rewarming. No significant difference in any of these variables was seen between the two types of flow. After conventional rewarming the temperature gradient between core tissues and muscle was not influenced by the type of flow used during rewarming.

摘要

10名接受低温体外循环的患者依次接受以下两种灌注:(1)滚压泵输送的标准流量,以及(2)由“搏动辅助装置”(Datascope公司,新泽西州帕拉默斯)诱导的搏动血流,两种灌注以随机顺序进行,平均流量相同。在每种血流类型期间以及复温后,测量全身氧耗、血乳酸浓度、全身血管阻力、尿流量和热梯度。两种血流类型之间在这些变量中均未观察到显著差异。常规复温后,核心组织与肌肉之间的温度梯度不受复温期间所用血流类型的影响。

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