Orecchia C, Sigaudo F, Ardizzone L, Sarasso E, Ciconi E, Rosso G, Grazioli O, Botta C, Adami A
Minerva Chir. 1980 Feb 15;35(3):111-8.
The treatment of perforated peptic ulcer, according to the experience of the Authors (327 cases), must be very pressing and always surgical. The closure of the perforation, the simplest treatment, seems the most suitable and the least dangerous for the survival of the patient, even though 68% of these patients will have to undergo surgery again in the course of 10 years. The radical treatment of resection, is reserved to few and carefully chosen cases, because it is loaded with sufficient risk. Acute bleeding peptic ulcer (86 cases) requires the operation: immediate or delayed according to the importance of the hemorrage: very serious, serious, moderate.
根据作者的经验（327例），穿孔性消化性溃疡的治疗必须非常紧迫，且始终需要手术治疗。穿孔闭合术作为最简单的治疗方法，似乎对患者的生存最为合适且风险最小，尽管这些患者中有68%在10年内将不得不再次接受手术。根治性切除术仅适用于少数经过精心挑选的病例，因为其风险较大。急性出血性消化性溃疡（86例）需要进行手术：根据出血的严重程度（非常严重、严重、中度）立即或延迟手术。
