Merlen J F, Coget J, Sarteel A M
Phlebologie. 1980 Jan-Mar;33(1):3-6.
The angiodysplasias represent a "disease of the vasculo-connective tissue system", the cells of the primitive area vasculosa being simultaneously histoblastic and haemoblastic. This accounts for the many facets of the clinical picture and the nosology. The slightest deviation in ontogenetic organization involves one or more malformations which embryology unfolds in the course of the various stages of development, provided that the importance of vasculo-connective tissue correlations and hydraulic factors is never forgotten. The problem of nosological classification is very difficult ; many have attempted it, including the School of Nancy with Kissel and André, that of Milan with Puglionisi, that of Schobinger and Leu, that of J. Natali... it remains to classify the clinical picture presented in one or another list.
血管发育异常代表一种“血管结缔组织系统疾病”,原始血管区域的细胞同时具有组织母细胞和血母细胞的特性。这就解释了临床表现和疾病分类学的诸多方面。个体发育组织中最轻微的偏差都会涉及一种或多种畸形,只要不忘血管结缔组织相关性和水力因素的重要性,胚胎学就会在发育的各个阶段展现这些畸形。疾病分类学的问题非常困难;许多人都尝试过,包括南锡学派的基塞尔和安德烈、米兰学派的普廖尼西、朔宾格和勒的学派、J. 纳塔利的学派……仍有待对在各种列表中呈现的临床表现进行分类。