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[心肌灌注闪烁显像和放射性核素血管造影术用于疑似冠心病门诊患者的评估]

[Myocardial perfusion scintigraphy and radionuclide angiography for the evaluation of outpatients with suspected coronary disease].

作者信息

Pfisterer M, Müller-Brand J, Bründler H, Fridrich R, Burkart F

出版信息

Schweiz Med Wochenschr. 1980 Mar 29;110(13):499-501.

PMID:7375901
Abstract

Combined ECG/myocardial perfusion szintigraphy (MPS) exercise tests were performed in 82 out-patients with suspected CAD who eventually underwent left heart catheterization. The sensitivity of MPS as compared to ECG was higher in patients with angina (86% vs. 67%) as well as in patients with atypical symptoms (63% vs. 25%). Here MPS was also more specific than ECG (86% vs. 68%). Combination of both tests improved sensitivity even more. The comparison of radionuclide and contrast ventriculography in 20 patients studied at rest revealed an excellent correlation (r = 0.90). Changes in radionuclide ejection fraction during exercise in 60 subjects showed significant differences between normals (increase of greater than 10% above resting level) and patients with CAD (decrease in patients with angina, no significant change without angina). Methods and indications are briefly discussed in the light of this experience.

摘要

对82例疑似冠心病的门诊患者进行了心电图/心肌灌注闪烁扫描(MPS)联合运动试验,这些患者最终接受了左心导管检查。与心电图相比,MPS在心绞痛患者(86%对67%)以及非典型症状患者(63%对25%)中的敏感性更高。在此,MPS也比心电图更具特异性(86%对68%)。两种检查相结合进一步提高了敏感性。对20例静息状态下研究的患者进行放射性核素与对比剂心室造影的比较,发现两者具有极好的相关性(r = 0.90)。60名受试者运动期间放射性核素射血分数的变化显示,正常人与冠心病患者之间存在显著差异(正常人高于静息水平增加超过10%,心绞痛患者降低,无心绞痛患者无显著变化)。根据这一经验简要讨论了方法和适应症。

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