Pfisterer M, Müller-Brand J, Bründler H, Fridrich R, Burkart F
Schweiz Med Wochenschr. 1980 Mar 29;110(13):499-501.
Combined ECG/myocardial perfusion szintigraphy (MPS) exercise tests were performed in 82 out-patients with suspected CAD who eventually underwent left heart catheterization. The sensitivity of MPS as compared to ECG was higher in patients with angina (86% vs. 67%) as well as in patients with atypical symptoms (63% vs. 25%). Here MPS was also more specific than ECG (86% vs. 68%). Combination of both tests improved sensitivity even more. The comparison of radionuclide and contrast ventriculography in 20 patients studied at rest revealed an excellent correlation (r = 0.90). Changes in radionuclide ejection fraction during exercise in 60 subjects showed significant differences between normals (increase of greater than 10% above resting level) and patients with CAD (decrease in patients with angina, no significant change without angina). Methods and indications are briefly discussed in the light of this experience.
对82例疑似冠心病的门诊患者进行了心电图/心肌灌注闪烁扫描(MPS)联合运动试验,这些患者最终接受了左心导管检查。与心电图相比,MPS在心绞痛患者(86%对67%)以及非典型症状患者(63%对25%)中的敏感性更高。在此,MPS也比心电图更具特异性(86%对68%)。两种检查相结合进一步提高了敏感性。对20例静息状态下研究的患者进行放射性核素与对比剂心室造影的比较,发现两者具有极好的相关性(r = 0.90)。60名受试者运动期间放射性核素射血分数的变化显示,正常人与冠心病患者之间存在显著差异(正常人高于静息水平增加超过10%,心绞痛患者降低,无心绞痛患者无显著变化)。根据这一经验简要讨论了方法和适应症。