Reigner P, Domenighetti G, Feihl F, Bonjour J P, Perret C
Schweiz Med Wochenschr. 1980 Feb 9;110(6):220-3.
The natural and treated course of Mycoplasma pneumoniae is generally satisfactory. Only a few cases with fatal outcome have been reported, mainly in immunosuppressed and debilitated patients. The case is reported of a healthy young woman admitted with acute respiratory failure, who developed diffuse interstitial fibrosing pneumonia followed by refractory hypoxemia. The diagnosis of Mycoplasma pneumoniae pneumonia was at first suspected from an elevated specific titer in the standard complement fixation test, and then confirmed in the immunofluorescence study by the presence of granular deposits (mycoplasma) in the macrophages of lung tissue. The functional impairments associated with this unusually malignant evolution are discussed.
肺炎支原体感染的自然病程及经治疗后的病程通常令人满意。仅有少数病例报告出现致命结局，主要见于免疫抑制和身体虚弱的患者。本文报告了一例健康年轻女性，因急性呼吸衰竭入院，随后发展为弥漫性间质性纤维化肺炎并伴有难治性低氧血症。起初，根据标准补体结合试验中特异性滴度升高怀疑为肺炎支原体肺炎，随后通过免疫荧光研究在肺组织巨噬细胞中发现颗粒状沉积物（支原体）得以确诊。文中还讨论了与这种异常恶性进展相关的功能损害。
