用人绒毛膜促性腺激素放射性抗体对癌症进行临床放射免疫检测。
Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.
作者信息
Goldenberg D M, Kim E E, DeLand F H, van Nagell J R, Javadpour N
出版信息
Science. 1980 Jun 13;208(4449):1284-6. doi: 10.1126/science.7375942.
Injection of iodine-131-labeled goat immunoglobulin G antibody to human chorionic gonadotropin (hCG) into patients with hCG-secreting trophoblastic and germinal tumors permitted tumor detection and location by external gamma-ray scintigraphy. Excision of one of the metastatic tumors located by this method indicated a tumor/nontumor ration of 39.29. The method appears to offer a new clinical tool for precisely locating hCG-producing tumors in the body, even when tumor identification by other clinical methods has failed.
向分泌人绒毛膜促性腺激素（hCG）的滋养层和生殖细胞瘤患者体内注射碘-131标记的抗人绒毛膜促性腺激素山羊免疫球蛋白G抗体，可通过体外γ射线闪烁扫描术检测肿瘤并确定其位置。通过该方法定位后切除的一个转移瘤显示肿瘤与非肿瘤组织的比例为39.29。即使其他临床方法无法识别肿瘤，该方法似乎也为精确确定体内产生hCG的肿瘤提供了一种新的临床工具。
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