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猫乳腺肿瘤和发育异常。基于个人研究得出的结论及对未来研究的一些建议。

Feline mammary tumours and dysplasias. Conclusions based on personal studies and some suggestions for future research.

作者信息

Weijer K

出版信息

Tijdschr Diergeneeskd. 1980 Apr 15;105(8):suppl 2:69-74.

PMID:7376173
Abstract

Feline mammary tumours and dysplasias were studied by various methods: morphological, electron-microscopical, immunotlogical and virological. The most important conclusion was that cats with mammary tumours (benign and malignant tumours and lesions, the significance of which is not known so far) may be suitable animal models for the study of certain features of human mammary tumours; for instance, the study of the relationship between particular histological and biological characteristics of mammary carcinoma and the prognosis; the study of the question whether a virus (or viruses) does (do) or does (do) not play a role in the pathogenesis or growth of mammary tumours; the study of the possible presence of specific cellular and/or humoral immunity to mammary tumours and the study of the possible effects of progestogens on the mammary gland. As the study can not be regarded as a self-contained entity, it should be continued; this applies particularly to those parts of the study, that offer the best prospects for comparative investigations.

摘要

通过多种方法对猫乳腺肿瘤和发育异常进行了研究

形态学、电子显微镜、免疫学和病毒学方法。最重要的结论是,患有乳腺肿瘤(良性和恶性肿瘤及病变,其意义目前尚不清楚)的猫可能是研究人类乳腺肿瘤某些特征的合适动物模型;例如,研究乳腺癌特定组织学和生物学特征与预后之间的关系;研究一种或多种病毒在乳腺肿瘤发病机制或生长中是否起作用的问题;研究对乳腺肿瘤可能存在的特异性细胞和/或体液免疫,以及研究孕激素对乳腺的可能影响。由于该研究不能被视为一个独立的实体,因此应该继续进行;这尤其适用于该研究中那些具有最佳比较研究前景的部分。

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