Andersen M, Lilja T, Lundell L, Thulin A
Acta Chir Scand. 1980;146(1):55-63.
In a retrospective study, clinical and laboratory findings in 454 patients subjected to laparotomy for suspected acute appendicitis were evaluated. A normal appendix was found in 25% of the total series and was twice as common in female as in male patients. Perforated appendicitis was present in 8% of the series, most commonly in the youngest (less than 5 years) and the oldest (greater than 40 years) age groups. The incidence of severe appendicitis increased with the duration of the preoperative abdominal symptoms. Of the patients with a 'laboratory profile' including fever and leukocytosis, 44% had gangrenous or perferated appendicitis. Of those who additionally had elevated ESR (greater than 20 mm), 62% showed a gangernous or perforated appendicitis. The overall incidence of wound infection was 13.9%. Wound infection was closely related to the state of the appendix. The results thus indicated that patient's age, duration of abdominal symptoms and the 'laboratory profile' are important parameters for assessment of clinically suspected acute appendicitis.
在一项回顾性研究中，对454例因疑似急性阑尾炎接受剖腹手术的患者的临床和实验室检查结果进行了评估。在全部病例中，25%的患者阑尾正常，且女性患者阑尾正常的情况是男性患者的两倍。该系列病例中8%存在穿孔性阑尾炎，最常见于最年幼（小于5岁）和最年长（大于40岁）的年龄组。重度阑尾炎的发病率随术前腹部症状持续时间的延长而增加。在有发热和白细胞增多等“实验室特征”的患者中，44%患有坏疽性或穿孔性阑尾炎。在那些血沉（ESR）也升高（大于20mm）的患者中，62%表现为坏疽性或穿孔性阑尾炎。伤口感染的总体发生率为13.9%。伤口感染与阑尾状况密切相关。因此，结果表明患者年龄、腹部症状持续时间和“实验室特征”是评估临床疑似急性阑尾炎的重要参数。
