Greiff J
Acta Orthop Scand. 1980 Feb;51(1):109-17. doi: 10.3109/17453678008990775.
A series of 14 patients who for various reasons were scheduled for total hip replacement were investigated. 99mTc-Sn-pyrophosphate scintigraphy and tetracycline labelling of the bone structure was performed prior to surgery, and subsequently the femoral heads were submitted to histological evaluation on decalcified as well as non-decalcified slides. The evaluation of the scintigraphs was performed by a specialist in nuclear medicine and the histological slides were evaluated by a pathologist, in both cases without reference to the radiological findings or the clinical history. The scintigraphic evaluations of the vitality of the femoral head were in all cases verified by the histological examination, whereas the radiological findings in three cases failed to demonstrate that a femoral head necrosis actually was present. From this study it can be concluded that 99mTc-Sn-pyrophosphate scintigraphy is an excellent method of assessing bone vitality in the femoral head.
对14例因各种原因计划进行全髋关节置换的患者进行了研究。术前进行了99mTc - 锡 - 焦磷酸盐闪烁扫描和骨结构的四环素标记，随后将股骨头在脱钙和未脱钙的载玻片上进行组织学评估。闪烁扫描图由核医学专家进行评估，组织学载玻片由病理学家评估，在这两种情况下均不参考放射学检查结果或临床病史。股骨头活力的闪烁扫描评估在所有病例中均通过组织学检查得到证实，而在3例中放射学检查结果未能显示股骨头坏死实际存在。从这项研究可以得出结论，99mTc - 锡 - 焦磷酸盐闪烁扫描是评估股骨头骨活力的一种优秀方法。
