Cabrera M A, Suazo A T
Bol Med Hosp Infant Mex. 1980 Mar-Apr;37(2):195-201.
The antibody titers for Toxocara and Ascaris were investigated in 49 patients of both sexes and hospitalized because of several pathological conditions, finding an 18% with high titer for Toxocara and 22% for Ascaris. Thirty-seven percent of those with positive titer for Ascaris showed ascaris eggs in the stool. Fifty-five percent of those with positive titer for Toxocara had had contact with dogs and cats and 33%, with dogs only. A correlation among the symptoms, chest x-ray, protein electrophoresis, relative eosinophilia and the elevation of antibodies could not be established; however, the patients with high titers for Ascaris and Toxocara showed an absolute eosinophilia higher than the mean. The diagnosis of systemic infection by larvae of Toxocara and Ascaris can be suspected when there is relative eosinophilia of 10% or more, but its confirmation is still difficult except when finding the parasite "in situ". The serological test can help, but it is not definitive. The recently developed tests are more sensitive and open new expectancies.
对49名因多种病理状况住院的男女患者进行了弓蛔虫和蛔虫抗体滴度的调查,发现18%的患者弓蛔虫抗体滴度高,22%的患者蛔虫抗体滴度高。蛔虫抗体滴度呈阳性的患者中,37%的人粪便中发现了蛔虫卵。弓蛔虫抗体滴度呈阳性的患者中,55%曾接触过狗和猫,33%仅接触过狗。症状、胸部X光、蛋白电泳、相对嗜酸性粒细胞增多症与抗体升高之间未发现相关性;然而,弓蛔虫和蛔虫抗体滴度高的患者绝对嗜酸性粒细胞增多高于平均值。当相对嗜酸性粒细胞增多达10%或更高时,可怀疑有弓蛔虫和蛔虫幼虫的全身感染,但除“在原位”发现寄生虫外,确诊仍很困难。血清学检测有帮助,但不具有决定性。最近开发的检测方法更敏感,带来了新的期望。