Karam Bechara J, Tapia Corredor R
Bol Med Hosp Infant Mex. 1980 Mar-Apr;37(2):301-8.
The pathophysiology of chronic bronchitis is not limited to pure infections as there may be a number of precipitating factors, like the air we breath, which is loaded with minute organic and inorganic particles that come into combination with soluble and insoluble gases penetrating through the respiratory ducts causing severe distant lesions or accumulation of secretions in upper respiratory tract that may be responsible for important disturbances in the ventilation producing repetition bronchitis. Such relationship is known as sinobronchial syndrome. This report includes 40 cases seen at the Hospital Infantil de México and studied in detail as to the pathophysiologic aspects. The results obtained were based on previous history, clinical picture, x-ray studies of paranasal sinuses and chest; bacteriological studies, hematologic and immunological aspects. The preschool age was the most frequent and males predominated over females. The outstanding symptom was coughing. Ten per cent of the patients were being treated as tuberculous and 8% as repetition amygdalitis. Out of the cases studied, 16 were operated (amygdalectomy) and out of these, antrostomy was done to 3, besides the administration of bronchodilators, antihistaminics, steroids and antibiotics of the penicillin type and derivatives.
慢性支气管炎的病理生理学并不局限于单纯的感染,因为可能存在许多诱发因素,比如我们呼吸的空气,其中充满了微小的有机和无机颗粒,这些颗粒与通过呼吸道渗透的可溶性和不溶性气体相结合,导致严重的远处病变或上呼吸道分泌物积聚,这可能是造成通气严重紊乱进而引发复发性支气管炎的原因。这种关系被称为鼻支气管综合征。本报告涵盖了在墨西哥儿童医院就诊的40例病例,并对其病理生理学方面进行了详细研究。所获得的结果基于既往病史、临床表现、鼻窦和胸部的X线检查、细菌学研究、血液学和免疫学方面。学龄前儿童最为常见,男性多于女性。突出症状为咳嗽。10%的患者被当作结核病治疗,8%被当作复发性扁桃体炎治疗。在所研究的病例中,16例接受了手术(扁桃体切除术),其中3例除了使用支气管扩张剂、抗组胺药、类固醇以及青霉素类及其衍生物抗生素外,还进行了鼻窦造口术。