吲哚美辛类似物的抗炎活性与其对兔多形核白细胞磷脂酶A2的抑制作用相关。 - Suppr

Suppr

超能文献

The antiinflammatory activity of analogs of indomethacin correlates with their inhibitory effects on phospholipase A2 of rabbit polymorphonuclear leukocytes.

作者信息

Kaplan-Harris L, Elsbach P

出版信息

Biochim Biophys Acta. 1980 May 28;618(2):318-26. doi: 10.1016/0005-2760(80)90038-7.

DOI:10.1016/0005-2760(80)90038-7

PMID:7378442

Abstract

摘要

相似文献

The antiinflammatory activity of analogs of indomethacin correlates with their inhibitory effects on phospholipase A2 of rabbit polymorphonuclear leukocytes.吲哚美辛类似物的抗炎活性与其对兔多形核白细胞磷脂酶A2的抑制作用相关。

Biochim Biophys Acta. 1980 May 28;618(2):318-26. doi: 10.1016/0005-2760(80)90038-7.

Effects of the anti-inflammatory serine esterase inhibitor, FOY, on phospholipase A2 (EC 3.1.1.4) activity in rabbit polymorphonuclear leukocytes.

Pharmacol Res Commun. 1983 Oct;15(9):869-78. doi: 10.1016/s0031-6989(83)80094-0.

Inhibition of highly purified mammalian phospholipases A2 by non-steroidal anti-inflammatory agents. Modulation by calcium ions.非甾体抗炎药对高度纯化的哺乳动物磷脂酶A2的抑制作用。钙离子的调节作用。

Biochem J. 1980 Feb 15;186(2):633-6. doi: 10.1042/bj1860633.

A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids.糖皮质激素诱导的兔中性粒细胞中的一种磷脂酶A2抑制蛋白。

Proc Natl Acad Sci U S A. 1980 May;77(5):2533-6. doi: 10.1073/pnas.77.5.2533.

Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes.低浓度的消炎痛抑制兔多形核白细胞的磷脂酶A2。

Proc Natl Acad Sci U S A. 1978 Jun;75(6):2955-8. doi: 10.1073/pnas.75.6.2955.

Studies on the incorporation of [1-14C]arachidonic acid into glycerolipids and its conversion into prostaglandins by rabbit iris. Effects of anti-inflammatory drugs and phospholipase A2 inhibitors.[1-14C]花生四烯酸掺入兔虹膜甘油脂质及其转化为前列腺素的研究。抗炎药和磷脂酶A2抑制剂的作用。

Biochim Biophys Acta. 1982 Jun 11;711(3):478-89. doi: 10.1016/0005-2760(82)90062-5.

Isolation of a human, endogenous, phospholipase A2 inhibitory, antiinflammatory protein.一种人源内源性磷脂酶A2抑制性抗炎蛋白的分离

Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:581-6.

Evidence for a direct inhibitory effect of glucocorticoids on the activity of phospholipase A2 as a further possible mechanism of some actions of steroidal anti-inflammatory drugs.

Pharmacol Res Commun. 1980 Sep;12(8):817-27. doi: 10.1016/s0031-6989(80)80085-3.

Inhibition of an inflammatory exudate phospholipase A2 by an endogenous inhibitor of polymorphonuclear leucocytes.多形核白细胞内源性抑制剂对炎性渗出物磷脂酶A2的抑制作用

Pharmacol Res Commun. 1982 May;14(5):401-7. doi: 10.1016/s0031-6989(82)80068-4.

Oligomers of prostaglandin B1 inhibit in vitro phospholipase A2 activity.前列腺素B1的寡聚体在体外抑制磷脂酶A2的活性。

Biochim Biophys Acta. 1989 Dec 18;1006(3):272-7. doi: 10.1016/0005-2760(89)90013-1.

引用本文的文献

Groups I, II and III extracellular phospholipases A2: selective inhibition of group II enzymes by indomethacin but not other NSAIDs.I、II和III组细胞外磷脂酶A2：吲哚美辛对II组酶有选择性抑制作用，而其他非甾体抗炎药则无此作用。

Agents Actions. 1994 Mar;41(1-2):111-3. doi: 10.1007/BF01986409.

How is the level of free arachidonic acid controlled in mammalian cells?哺乳动物细胞中游离花生四烯酸的水平是如何控制的？

Biochem J. 1982 Apr 15;204(1):3-16. doi: 10.1042/bj2040003.

Protein synthesis in isolated rabbit forelimb muscles. The possible role of metabolites of arachidonic acid in the response to intermittent stretching.兔离体前肢肌肉中的蛋白质合成。花生四烯酸代谢产物在间歇性拉伸反应中的可能作用。

Biochem J. 1983 Jul 15;214(1):153-61. doi: 10.1042/bj2140153.

Metabolites of arachidonic acid.花生四烯酸的代谢产物

Clin Rev Allergy. 1983 Sep;1(3):369-84. doi: 10.1007/BF02991227.

Transfer of arachidonate from phosphatidylcholine to phosphatidylethanolamine and triacylglycerol in guinea pig alveolar macrophages.花生四烯酸在豚鼠肺泡巨噬细胞中从磷脂酰胆碱向磷脂酰乙醇胺和三酰甘油的转移。

Lipids. 1986 Oct;21(10):623-8. doi: 10.1007/BF02537210.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验