Spontaneous regression of metastatic testicular carcinoma in a patient with bilateral sequential testicular tumor.

Spontaneous regression of metastatic neoplasia is rate. A review of previously reported spontaneous regressions of testicular cancer indicates that in no case has such a patient had a prior, concurrent, or subsequent contralateral tumor. The case presented is unusual because it is the first instance of bilateral sequential testicular cancer in which spontaneous regression of metastases from one of the tumors has been noted. Together with a previous report of a spontaneous regression of testicular cancer which occurred only after a second orchiectomy, the present case suggests the possibility of hormonal modulation of tumor growth.