苯妥英钠-米索硝唑：可能的代谢相互作用。
Phenytoin-misonidazole: possible metabolic interaction.
作者信息
Gangji D, Schwade J G, Strong J M
出版信息
Cancer Treat Rep. 1980 Jan;64(1):155-6.
PMID:7379050
Abstract
Following iv administration of misonidazole, evidence of decreased plasma half-life (3.8 hours versus 9.1 hours +/- 0.8 [SD] in eight other patients studied) and increased metabolism was observed in a patient receiving continuous phenytoin therapy.
摘要
在静脉注射米索硝唑后，在一名接受苯妥英持续治疗的患者中观察到血浆半衰期缩短（在其他8名研究患者中为3.8小时，而其他患者为9.1小时±0.8[标准差]）以及代谢增加的证据。
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