Gittenberger-de Groot A C, Moulaert A J, Hitchcock J F
Circulation. 1980 Jul;62(1):183-6. doi: 10.1161/01.cir.62.1.183.
Histologic study of the persistent ductus arteriosus in case of a congenital rubella syndrome revealed that this persistency is probably due to an arrest in the development of the ductus. Histologically, it resembles a very immature ductus and not the most common type of persistent ductus arteriosus. The earlier finding, that in the human ductus arteriosus, the presence of an extensive subendothelial elastic lamina is incompatible with anatomic sealing, still holds.
对先天性风疹综合征病例中持续存在的动脉导管进行组织学研究发现,这种持续性可能是由于动脉导管发育停滞所致。从组织学上看,它类似于非常不成熟的动脉导管,而非最常见类型的持续性动脉导管。早期的发现,即在人类动脉导管中,广泛的内皮下弹性膜的存在与解剖学上的闭合不相容,这一点仍然成立。