成年大鼠心脏单个心肌细胞的电压钳法
Voltage clamp method on single cardiac cells from adult rat heart.
作者信息
Undrovinas A I, Yushmanova A V, Hering S, Rosenshtraukh L V
出版信息
Experientia. 1980 May 15;36(5):572-4. doi: 10.1007/BF01965808.
PMID:7379958
Abstract
Voltage clamp experiments on isolated cardiac cells from adult rat hearts were carried out using an intracellular dialysis method. The fast inward current was recorded. Tetrodotoxin (TTX) at a concentration of 2.5 x 10(-7) g/ml blocked this current to 30% of its initial value. Inward maximal fast current density was calculated to be 0.14--0.7 mA/cm2.
摘要
采用细胞内透析法对成年大鼠心脏分离的心肌细胞进行电压钳实验。记录快速内向电流。浓度为2.5×10⁻⁷g/ml的河豚毒素（TTX）将该电流阻断至其初始值的30%。计算得出内向最大快速电流密度为0.14 - 0.7 mA/cm²。
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