Sabattini L, Piazza G C, Finizio F S
J Neurosurg Sci. 1980 Jan-Mar;24(1):33-6.
On the basis of a 4 year experience with CT scan in cerebral gliomas and of previous personal contributions in this field, a neuroradiological protocol of these patients is proposed. The protocol consists of a complete preoperative neuroradiological evaluation and of CT assessments at the end of the surgical procedure, before initiating radio-chemotherapy, and at the completion of each of its cycles, respectively. Attention is drawn to the importance of contrast enhancement, to the role played by the changes in the blood-brain barrier (BBB), either due to surgery or to the effect of radio-chemotherapy and to the identification of residual tumor or of recurrences. CT scan to be performed at the end of the operation is proposed on the assumption that, in spite of the increased possibility of artifacts due to blood, air, etc., it may provide an immediate and better evaluation of the surgical results as compared to the CT picture at the beginning of radio-chemotherapy, when changes in the patient's brain may already have occurred.
基于对脑胶质瘤患者进行4年CT扫描的经验以及本人此前在该领域的研究成果，现提出针对这些患者的神经放射学检查方案。该方案包括完整的术前神经放射学评估，以及在手术结束时、开始放化疗前、放化疗每个周期结束时分别进行的CT评估。重点关注增强扫描的重要性、血脑屏障（BBB）变化所起的作用，这种变化可能由手术或放化疗的影响所致，同时关注残余肿瘤或复发的识别。建议在手术结束时进行CT扫描，理由是尽管由于血液、空气等因素导致伪影增加的可能性较大，但与放化疗开始时的CT图像相比，此时的CT扫描可能会提供对手术结果的即时且更好的评估，因为那时患者脑部可能已经发生了变化。
