JAMA. 1980 Jul 18;244(3):259-63.
The brain is particularly vulnerable to insults occurring anywhere in the body. In some older persons, the brain may respond to insult by slowly developing impairment of intellectual functions (dementia) or abruptly showing significant changes in mental state (delirium). Sometimes the two coincide, producing a variable clinical picture with features of both dementia and delirium. It is crucial for health professionals, public planners, and lay persons to recognize that many curable physical and psychological diseases in the elderly produce intellectual impairment that may be hard to distinguish from irreversible brain disease.
大脑特别容易受到身体其他部位发生的损伤的影响。在一些老年人中,大脑可能会通过智力功能缓慢衰退(痴呆)或精神状态突然出现显著变化(谵妄)来应对损伤。有时这两种情况会同时出现,产生兼具痴呆和谵妄特征的复杂临床表现。对于医疗专业人员、公共规划者和普通大众来说,认识到老年人中许多可治愈的身体和心理疾病会导致智力障碍,且这种障碍可能难以与不可逆的脑部疾病区分开来至关重要。