Farina G P, Azara P, Scintu F, Pisano G, Tagliacozzo S
Minerva Chir. 1980 May 15;35(9):619-26.
A personal series of 176 thrombo-embolisms in the extremities, 157 of them operated, observed at the Surgical Clinic of Cagliari University in the period 1969-1977, is reported. The results of surgery are discussed in relation to the factors which most affect prognosis: age, time and degree of ischaemia, anatomo-pathological condition of the arteries and site of obstruction. Severe ischaemia poses the problem of indication for disobstruction: the possible onset of the revascularization syndrome, which almost always causes the death of the patient, should be borne in mind. Recently proposed local wash-out techniques do not complete solve the problem because although they manage to prevent the revascularization syndrome, they do not always save the extremity, which has to be amputated at a later stage after pointless risks to the patient. On the other hand, the poor functional results obtainable from an extremity that has suffered severe ischaemia must be considered. It is therefore preferred to forgo disobstruction when the ischaemia is so serious that revascularization syndrome is probable.
本文报告了1969年至1977年期间在卡利亚里大学外科诊所观察到的176例肢体血栓栓塞病例,其中157例接受了手术治疗。结合影响预后的主要因素,即年龄、缺血时间和程度、动脉解剖病理状况以及梗阻部位,对手术结果进行了讨论。严重缺血引发了血管再通指征的问题:应牢记血管再通综合征的可能发生,该综合征几乎总会导致患者死亡。最近提出的局部冲洗技术并未完全解决问题,因为尽管它们设法预防了血管再通综合征,但并不总能挽救肢体,肢体在给患者带来无意义风险后,后期仍不得不进行截肢。另一方面,必须考虑严重缺血肢体所能获得的不良功能结果。因此,当缺血严重到可能发生血管再通综合征时,最好放弃血管再通。