Soules M R, Hughes C L, Garcia J A, Livengood C H, Prystowsky M R, Alexander E
Obstet Gynecol. 1980 Jun;55(6):696-700.
Although nausea and vomiting associated with early pregnancy are extremely common, the causal factors remain obscure. An endocrine etiology for this problem persists as a popular but unproved theory. The present study exn (hCG) and 17-hydroxyprogesterone (17-OHP) and the presence or severity of nausea and/or vomiting in women in the first 16 weeks of pregnancy. The occurrence and severity of nausea and/or vomiting in women with hydatidiform moles in relation to serum hCG levels were also investigated. Levels of hCG and 17-OHP in pregnant women grouped on the basis of severity of nausea and vomiting are compared to each other and to the levels found in normal pregnancies. No relationship could be established between the levels of hCG and 17-OHP and the incidence and severity of nausea and vomiting in either pregnant patients or in women with molar pregnancies.
尽管与早孕相关的恶心和呕吐极为常见，但其病因仍不清楚。关于这一问题的内分泌病因仍然是一种流行但未经证实的理论。本研究检测了妊娠前16周女性血清人绒毛膜促性腺激素（hCG）和17-羟孕酮（17-OHP），以及恶心和/或呕吐的存在情况或严重程度。还研究了葡萄胎女性恶心和/或呕吐的发生情况及严重程度与血清hCG水平的关系。将根据恶心和呕吐严重程度分组的孕妇的hCG和17-OHP水平相互比较，并与正常妊娠中的水平进行比较。在妊娠患者或葡萄胎妊娠女性中，hCG和17-OHP水平与恶心和呕吐的发生率及严重程度之间均未发现相关性。
