Boehm F H, Killam A P, Chambers J F, Davidson K K
Obstet Gynecol. 1980 Jun;55(6):758-60.
Three patients with anencephalic fetuses were delivered vaginally following use of prostaglandin E2 (PGE2) vaginal suppositories with minimal side effects and minimal delay until delivery, even though the cervix was unfavorable. One patient had laminaria inserted 12 hours prior to a single PGE2 suppository. The fetuses were stillborn, although all had had fetal heart tones when the first suppository was inserted. The observed uterine tachysystole and hypertonus under these circumstances may be advantageous if they prevent the additional emotional stress involved with the birth of a "live" anencephalic infant.
三名无脑儿胎儿的孕妇在使用前列腺素E2（PGE2）阴道栓剂后经阴道分娩，副作用极小，分娩延迟极短，尽管宫颈条件不佳。一名患者在使用单一PGE2栓剂前12小时插入了海藻棒。胎儿均为死产，尽管在插入第一个栓剂时所有胎儿都有胎心音。在这种情况下观察到的子宫快速收缩和张力过高可能是有利的，因为它们可避免与“活产”无脑儿出生相关的额外精神压力。
