Schreiber A D
Pediatr Clin North Am. 1980 May;27(2):253-67. doi: 10.1016/s0031-3955(16)33850-0.
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells. The importance of complement in the destruction of IgM-coated cells has also been recognized.
在自身免疫性溶血性贫血中，个体产生针对自身红细胞膜抗原之一的抗体。自身免疫性溶血性贫血中的溶血最常见于血管外而非血管内，肝脏和脾脏在清除抗体包被细胞方面起主要作用。补体在破坏IgM包被细胞中的重要性也已得到认可。
