Grieco M B, Cady B
Surg Clin North Am. 1980 Apr;60(2):369-79. doi: 10.1016/s0039-6109(16)42086-4.
Staging laparotomy is a useful procedure as long as regional radiotherapy continues to be the primary modality of treatment for early Hodgkin's disease. However, many oncologists have extended the indications for systemic chemotherapeutic agents. Studies are in progress to evaluate the effectiveness of chemotherapy alone for all patients with B symptoms as well as for those with stages I and II disease associated with large mediastinal masses or lymphocyte depletion histology. If therapeutic practices change significantly in the future, there may be fewer indications for careful staging. The natural history of treatment of cancers in a sophisticated therapeutic environment is that more careful staging is required to utilize the vast array of therapies being developed to improve prognosis. In all likelihood staging laparotomy in some form will continue to be a part of the management scheme for patients with Hodgkin's disease.
只要区域放射治疗仍是早期霍奇金病的主要治疗方式，分期剖腹术就是一种有用的程序。然而，许多肿瘤学家已经扩大了全身化疗药物的适应证。目前正在进行研究，以评估单纯化疗对所有有B症状的患者以及对伴有大纵隔肿块或淋巴细胞消减型组织学的Ⅰ期和Ⅱ期疾病患者的有效性。如果未来治疗方法发生显著变化，可能就会减少仔细分期的适应证。在复杂的治疗环境中，癌症治疗的自然过程是，需要更仔细的分期来利用为改善预后而开发的大量治疗方法。很有可能某种形式的分期剖腹术将继续作为霍奇金病患者管理方案的一部分。
