[State of blood acid-base balance of the normal pregnant woman, fetus and newborn and with hypoxia and certain aspects of its regulation].

A dependence is studied between changes in the HCO3- and CO2 levels, the content of pyruvate and lactate in blood and the manifestation of disturbances of external respiration in pregnant women suffering from the rheumatic and congenital heart disease. Changes in the carbonic acid level in the blood of pregnant women with pathology of the cardiovascular system correlate reliably, with the frequency and gravity of complications in the course of pregnancy, labour, the state of the fetus and newborn. Some modern methods are considered for regulating acid-base balance, their brief critical analysis is presented with the view of using them in the obstetric practice. Possibility of carbostimulin application in hypoxic states of the mother, fetus and newborn is discussed.