Kotliar B I, Ovcharenko Iu S
Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Jan-Feb;30(1):169-76.
A new cellular analog of temporary connection has been elaborated on a micropool of neurones in the sensorimotor cortex. Transmitters -- glutamate and acetylcholine, microionophoretically applied near studied neurones, served as paired signals. In case of initial reactivity to paired stimuli, a stronger excitatory effect of the US analog in comparison to that of the CS analog, all studied neurones of the micropopulation developed, within the area of the transmitters' action (less than 100 mc), specific associative rearrangements: enhancement in reactivity to the signal stimulus and reproduction of the reaction to US in response to CS. In control experiments with pseudoconditioning and reverse order of presentation of the same paired stimuli, no rearrangement was observed.
在感觉运动皮层的一个微神经元池上构建了一种新的临时连接的细胞类似物。通过微离子电泳法在被研究神经元附近施加的递质——谷氨酸和乙酰胆碱,作为配对信号。如果对配对刺激有初始反应性,与条件刺激类似物相比,非条件刺激类似物具有更强的兴奋作用,那么在递质作用区域(小于100立方微米)内,该微群体中所有被研究的神经元都会发生特定的联想重排:对信号刺激的反应性增强,并且在条件刺激作用下重现对非条件刺激的反应。在假条件反射和相同配对刺激呈现顺序颠倒的对照实验中,未观察到重排现象。