Scheinmann P, Lebel B, Canu P, Burtin C
Agents Actions. 1980 Apr;10(1 Pt 2):150-1. doi: 10.1007/BF02024201.
The influence of castration on histamine levels in mouse tissues was investigated in Swiss mice. Only in female mice castration led to a significant decrease in the histamine content of dorsal and ventral skin, skeletal muscle and kidney. This effect was found 2 weeks after castration. A long-term study is being presently undertaken.