Wolff S M
Hosp Pract. 1978 Nov;13(11):113-5, 120-3. doi: 10.1080/21548331.1978.11707436.
The recent discovery that an age-old drug, colchicine, can control this enigmatic, often unrecognized, recurrent disease means that most affected individuals can now lead virtually normal lives. The research leading to this advance is described, as are the essentials of diagnosis, colchicine's possible mechanisms of action, and the relative merits of chronic vs intermittent colchicine therapy in the abortion of impending attacks.
最近发现，一种古老的药物秋水仙碱能够控制这种神秘的、常常未被识别的复发性疾病，这意味着大多数患者现在几乎可以过上正常生活。本文描述了促成这一进展的研究，以及诊断要点、秋水仙碱可能的作用机制，以及在即将发作时使用秋水仙碱进行慢性治疗与间歇性治疗的相对优点。
