Karakousis C P, Seddiq M K, Moore R
Arch Surg. 1980 Jun;115(6):719-22. doi: 10.1001/archsurg.1980.01380060021006.
Retrospective review of 199 patients with malignant melanoma who had regional node dissection showed that the median survival rates of patients with histologically negative nodes was more than threefold higher than that of patients with histologically positive regional nodes. In the patients with positive nodes, survival was related to the number of nodes involved. Patients with one, two, and three or more positive lymph nodes had a tumor-free five-year survival rate of 41%, 30%, and 18%. Patients who required regional node dissection for positive palpable nodes in one month, one year, or longer than one year from the excision of the primary tumor had a median survival of 21.5, 22, and 44 months.
对199例行区域淋巴结清扫术的恶性黑色素瘤患者进行回顾性研究发现，组织学检查淋巴结阴性的患者的中位生存率比区域淋巴结组织学检查阳性的患者高出三倍多。在淋巴结阳性的患者中，生存率与受累淋巴结的数量有关。有1个、2个以及3个或更多阳性淋巴结的患者的无瘤五年生存率分别为41%、30%和18%。在原发肿瘤切除后1个月、1年或超过1年因可触及的阳性淋巴结而需要进行区域淋巴结清扫术的患者，其中位生存期分别为21.5个月、22个月和44个月。
