Austin D F
Arch Otolaryngol. 1980 Jul;106(7):377-82. doi: 10.1001/archotol.1980.00790310001001.
In a long-term study of the treatment of Meniere's disease, 105 cases treated from 1965 through 1973 were divided into subgroups by virtue of the institution of routine polytomographic examination of the vestibular aqueduct (1968). A comparison of results of treatment in the two groups (empiric indication of endolymphatic shunt vs x-ray film evidence) yielded the following conclusions: (1) Success or failure of the endolymphatic shunt operation is significantly correlated with patency or obliteration of the vestibular aqueduct as seen on roentgenographic examination. (2) To be effective, medical therapy must be instituted early, when fluctuant hearing is the primary symptom. (3) More severe cases with roentgenographically obliterated vestibular aqueducts and unrelenting vertigo are best treated with vestibular nerve section via middle fossa craniotomy. (4) More precise definition of pathogenesis is needed to define the disease at onset, so that early definitive therapy may be designed.
在一项关于梅尼埃病治疗的长期研究中，1965年至1973年期间治疗的105例患者根据前庭导水管常规体层摄影检查的实施情况（1968年）被分为亚组。对两组治疗结果（内淋巴分流术的经验性指征与X线片证据）进行比较，得出以下结论：（1）内淋巴分流术的成功或失败与X线检查所见的前庭导水管通畅或闭塞显著相关。（2）要想有效，药物治疗必须在波动性听力为主要症状时尽早开始。（3）对于X线检查显示前庭导水管闭塞且眩晕持续不缓解的更严重病例，最好通过中颅窝开颅术进行前庭神经切断术。（4）需要更精确地定义发病机制，以便在疾病发作时对其进行界定，从而设计出早期确定性治疗方案。
