Meisel P, Amon I, Hüller H, Jährig K
Biol Neonate. 1980;38(1-2):30-5. doi: 10.1159/000241323.
Under in vitro conditions, theophylline accelerates the rate of bilirubin photodestuction sensitized by riboflavin, but does not do so in absence of this dye. The effect depends on the concentrations of theophylline and/or riboflavin, on the bilirubin/albumin ratio, and seems to implicate bilirubin unbound to serum albumin. Possible causes of the theophylline action and clinical implication regarding thephototherapy of neonatal jaundice are discussed.
在体外条件下，茶碱可加速核黄素致敏的胆红素光破坏速率，但在没有这种染料时则不会。该效应取决于茶碱和/或核黄素的浓度、胆红素/白蛋白比值，似乎与未与血清白蛋白结合的胆红素有关。本文讨论了茶碱作用的可能原因以及与新生儿黄疸光疗的临床意义。
