Aarnoudse J G, Oeseburg B, Kwant G, Huisjes H J, Zijlstra W G
Biol Neonate. 1980;38(1-2):49-60. doi: 10.1159/000241331.
Scalp tissue PO2, carotid arterial PO2 fetal heart rate were continuously measured in the anaesthetized fetal lamb in utero while variations in oxygen supply were brought about. In some experiments the transcutaneously measured fetal scalp PO2 was recorded in addition. Scalp tissue PO2 was measured using specially designed miniature needle-type oxygen electrode, incorporated in an easily applicable spiral scalp electrode as commonly used for fetal heart rate monitoring. The measurements showed that fetal carotid arterial hypoxaemia is always nearly immediately followed by fetal scalp tissue hypoxia, and that the recovery of scalp tissue PO2 after a hypoxic period has a remarkably varying time course. Fetal heart rate usually decreased during hypoxia, but in some instances it did not change or even increased, demonstrating that heart rate is not always a reliable indicator of fetal hypoxia. PO2 values obtained with the transcutaneous method were higher than those with the needle electrode, because of the effect of the heating system of the transcutaneous electrode on tissue blood flow and haemoglobin oxygen affinity. It would seem that during hypoxaemia the decrease in scalp tissue PO2 is poossibly the combined result of the fall in arterial PO2 and a concomitant decrease in blood flow through the skin.
在子宫内麻醉的胎羊身上，当改变氧气供应时，持续测量头皮组织的氧分压（PO2）、颈动脉血氧分压和胎儿心率。在一些实验中，还记录经皮测量的胎儿头皮PO2。头皮组织PO2使用专门设计的微型针型氧电极进行测量，该电极集成在一个易于应用的螺旋头皮电极中，这种电极常用于胎儿心率监测。测量结果表明，胎儿颈动脉低氧血症几乎总是紧接着胎儿头皮组织缺氧出现，并且缺氧期后头皮组织PO2的恢复具有明显不同的时间进程。胎儿心率在缺氧期间通常会下降，但在某些情况下它没有变化甚至增加，这表明心率并不总是胎儿缺氧的可靠指标。由于经皮电极的加热系统对组织血流和血红蛋白氧亲和力的影响，经皮方法获得的PO2值高于针电极测量的值。似乎在低氧血症期间，头皮组织PO2的下降可能是动脉PO2下降和伴随的皮肤血流减少的综合结果。
