[Changes in glycogenolysis in the ischemic zone in experimental myocardial infarct].

The first minutes of coronary artery occlusion in dogs showed the enhancement of glycogenolysis which was provided by the activation of phosphorylase, phosphofructokinase, triosophosphate isomerase and lactate dehydrogenase. The aldolase and glyceroaldehyde-3-phosphate dehydrogenase reactions were the rate limiting steps. The activation of glycogenolysis seems to be the result of a combined action of hypoxia and catecholamines.