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[Effect of antihepatocytotoxic serum on processes of cellular and intracellular regeneration of pathologically altered liver].

作者信息

Il'chevich N V, Alekseeva I N, Bryzgina T M, Bezprozvannyĭ B K, Galenko T I

出版信息

Biull Eksp Biol Med. 1980 Mar;89(3):368-70.

PMID:7388150
Abstract

The parameters of the liver regeneration: mitotic index, DNA synthesis, nucleolar size of hepatocytes and histological structure, were studied in adult female rats with CCl4-affected liver during administration of the gamma-globulin fraction of antihepatocytotoxic serum (gamma-AHCS). It was shown that in various periods after exposure to CCl4 either the cellular processes of regeneration are predominant or the intracellular ones. gamma-AHCS (0.06 microgram protein per 100g body weight/one injection) intensifies and makes longer both the processes.

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