Rees W V, Robinson D S, Holmes E C, Morton D L
Cancer. 1980 Jun 15;45(12):3045-9. doi: 10.1002/1097-0142(19800615)45:12<3045::aid-cncr2820451228>3.0.co;2-y.
Radionucleotide scanning with colloidal 198Au and 99Tc sulfur colloid was used to evaluate preoperative and postoperative lymphatic drainage in 10 patients with primary malignant melanoma of the trunk. After an intradermal injection of radionucleotide aroung the primary melanoma site, tomographic scanning was performed to identify the regional lymph nodes to which the radionucleotide drained. Approximately one year following lymphadenectomy, each patient was rescanned to see if the lymphatic drainage had changed. Of the 10 patients tested, 8 had postoperative drainage patterns that differed from the preoperative scans. Three patients had no drainage to the lymphadenectomy site, which two patients retained some drainage to the lymphadenectomy sites but also showed drainage to a new site. One patient retained drainage to only one of two preoperative sites, and 2 patients had no identifiable lymphatic drainage postoperatively. Thus, interruption of lymphatic channels is temporary, and new routes that may differ from preoperative ones generally develop within one to two years.
采用胶体198金和99锝硫胶体进行放射性核素扫描，以评估10例躯干原发性恶性黑色素瘤患者术前和术后的淋巴引流情况。在原发性黑色素瘤部位周围皮内注射放射性核素后，进行断层扫描以确定放射性核素引流至的区域淋巴结。在淋巴结切除术后约一年，对每位患者进行再次扫描，以观察淋巴引流是否发生变化。在接受检测的10例患者中，8例患者术后的引流模式与术前扫描结果不同。3例患者的淋巴未引流至淋巴结切除部位，2例患者仍有部分淋巴引流至淋巴结切除部位，但也显示有淋巴引流至新的部位。1例患者仅保留了术前两个部位中一个部位的淋巴引流，2例患者术后未发现可识别的淋巴引流。因此，淋巴通道的中断是暂时的，通常会在一到两年内形成与术前不同的新途径。
