Kimura S
Dermatologica. 1980;160(6):390-7. doi: 10.1159/000250528.
5 cases of condylomata acuminata with pigmented papular lesions were examined. By light microscopy, the pigmented papules showed benign basaloid cell proliferation and papillomatosis with only a few vacuolizations of the keratinocytes. Although mitotic figures increased in number, cellular atypia and disorderly arrangement were rarely observed. Electron microscopy revealed only benign epidermal cell proliferation. From these findings, the pigmented papules may be regarded as an initial stage or a forme fruste of condylomata acuminata. These papules are clinically very similar to the lesions of so-called multicentric pigmented Bowen's disease and the relationships between these two conditions are discussed.
对5例伴有色素性丘疹病变的尖锐湿疣进行了检查。光镜下,色素性丘疹表现为良性基底样细胞增生和乳头瘤病,仅角质形成细胞有少量空泡化。虽然有丝分裂象数量增加,但很少观察到细胞异型性和排列紊乱。电子显微镜检查仅显示良性表皮细胞增生。根据这些发现,色素性丘疹可被视为尖锐湿疣的初始阶段或顿挫型。这些丘疹在临床上与所谓的多中心色素性鲍温病的病变非常相似,并对这两种情况之间的关系进行了讨论。