羧肽酶消化对大肠杆菌素E3功能的影响。

The effects of carboxypeptidase digestion on the function of colicin E3.

作者信息

Ohno S, Saito K, Suzuki K, Imahori K

出版信息

J Biochem. 1980 Mar;87(3):989-92. doi: 10.1093/oxfordjournals.jbchem.a132830.

DOI:10.1093/oxfordjournals.jbchem.a132830

Abstract

The effects of carboxypeptidase digestion on the function of colcin E3 which had been demonstrated to be a complex of proteins A and B was investigated. It was indicated that removal of 7 amino acids from the C-terminal region of protein A has no significant effect on the interaction with the inhibitor, protein B, or with the specific cell surface receptor but does have an effect on the efficient interaction with the final target, ribosomes.

摘要

研究了羧肽酶消化对已被证明是蛋白质A和B复合物的秋水仙碱E3功能的影响。结果表明，从蛋白质A的C末端区域去除7个氨基酸对与抑制剂蛋白质B或与特定细胞表面受体的相互作用没有显著影响，但对与最终靶标核糖体的有效相互作用有影响。