González Espínola G, Esquivel López A, García Garduño J R, Valenzuela Tamariz J, Guerrero Hernández M
Rev Gastroenterol Mex. 1980 Jan-Mar;45(1):11-5.
A prospective and comparative study between the citology obtained through gastric washing and endoscopic (biopsy and brushing) for the diagnostic of the gastric neoplasias was carried at the Hospital de Especialidades del Centro Médico La Raza. Twenty one patients with benign gastric ulcer and 18 patients with gastric neoplasia (Two lymphomas and 16 adenocarcinomas) which we checked through surgery, necropsy or clinic evolution were studied. From 21 cases of gastric ulcer, the washing produced enough material for diagnosis in 17 of them (81%); in 16 of these neoplasia was excluded (94.1%) with false positive (5.9%). The endoscopic regained 100% of useful material and in a 100% ignored neoplasia. From 18 neoplasia cases, gastric washing produced material for 14 of them (77.8%); in 10 of these (71.4%) it made a diagnostic with 4 false negatives (28.6%); Endoscopic collected material in a 100% and the accuracy diagnostic was of 17 (94.4%) with one false negative (5.6%). Gastric washing has a high index of uselless for diagnostic from 39 samples, 8 were useless and from these, autolisis was the mein cause. Citology through gastric washing is usefull for neoplasm diagnosis in those cases in which endoscopy would be contraindicated or in those in which it is absent.
在拉腊扎医疗中心专科医院开展了一项前瞻性对比研究,比较通过洗胃获取的细胞学检查结果与内镜检查(活检和刷检)结果对胃肿瘤的诊断价值。研究对象为21例良性胃溃疡患者和18例胃肿瘤患者(2例淋巴瘤和16例腺癌),这些患者均通过手术、尸检或临床病程进行了检查。在21例胃溃疡病例中,洗胃获取的样本有17例(81%)足以用于诊断;其中16例(94.1%)排除了肿瘤,假阳性率为5.9%。内镜检查获取有效样本的比例为100%,且100%排除了肿瘤。在18例肿瘤病例中,洗胃获取样本的有14例(77.8%);其中10例(71.4%)做出了诊断,假阴性率为28.6%;内镜检查样本获取率为100%,诊断准确率为17例(94.4%),假阴性率为5.6%。从39份样本来看,洗胃诊断的无用率较高,有8份无用,其中自溶是主要原因。对于那些内镜检查禁忌或无法进行内镜检查的病例,洗胃细胞学检查对肿瘤诊断有用。