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[持续性腹膜透析中的临床化学参数]

[Clinical chemistry parameters in continuous peritoneal dialysis].

作者信息

Jung N, Karátson A, Thieler H, Baufeld A, Schmidt U

出版信息

Z Gesamte Inn Med. 1980 Feb 1;35(3):123-6.

PMID:7395293
Abstract

The continuous peritoneal dialysis (CAPD) is with four or five change of 1 1/2-2 l dialysis solution a day a 24 hours/day and 7 days/week dialysis. In 6 patients with terminal renal insufficiency the behaviour of biochemical parameters which serve as acknowledged indicators for the efficiency of a dialysis technique, were pursued under this method more than 4 weeks. At the end of the treatment period the following average values came up: creatinine 9.0 mg/dl, urea-N 65 mg/dl, anorganic phosphate 4.8 mg/dl (without Al-hydroxide), potassium 4.3 mval/l, calcium 4.1 mval/l and a pH-value of 7.35. The results allow the conclusion that with the CAPD a sufficient elimination of retention products is possible and values in the suburaemic region may be achieved similar to the conditions in the intermittent dialytic technique. Conclusions concerning a broad application of the technique in the terminal renal insufficiency may, however, not be made alone from these observations, since the problems of relapsing peritonitis and of the chronic loss of protein known from literature did not yet play a role in our patients in the short observation period.

摘要

持续性非卧床腹膜透析(CAPD)是每天进行4至5次1.5至2升透析液的更换,每周7天、每天24小时进行透析。对6例终末期肾功能不全患者采用该方法进行了4周以上的观察,追踪了作为公认的透析技术效率指标的生化参数变化情况。在治疗期末得到了以下平均值:肌酐9.0毫克/分升,尿素氮65毫克/分升,无机磷4.8毫克/分升(未服用氢氧化铝时),钾4.3毫当量/升,钙4.1毫当量/升,pH值7.35。这些结果表明,采用CAPD能够充分清除潴留产物,并且可以达到与间歇性透析技术类似的亚尿毒症区域数值。然而,仅根据这些观察结果尚不能得出该技术可广泛应用于终末期肾功能不全的结论,因为在短观察期内,文献中已知的复发性腹膜炎和慢性蛋白质丢失问题在我们的患者中尚未出现。

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