Haslam P L, Townsend P J, Branthwaite M A
Anaesthesia. 1980 Jan;35(1):22-6. doi: 10.1111/j.1365-2044.1980.tb03715.x.
Conversion of C3, the third component of complement, has been studied using a two-dimensional immunoelectrophoretic method. Evidence of C3 conversion has been obtained in stored donor blood, in patients during and after cardiac surgery involving cardiopulmonary bypass, and occasionally during thoractomy for pulmonary resection. It is suggested that complement activation is one factor contributing to tissue injury after cardiopulmonary bypass.
运用二维免疫电泳法对补体第三成分C3的转化进行了研究。在储存的供血者血液中、在进行体外循环心脏手术的患者术中及术后，以及偶尔在肺切除开胸手术过程中，均已获得C3转化的证据。提示补体激活是体外循环后导致组织损伤的一个因素。
