Fisher M M
Anaesth Intensive Care. 1980 May;8(2):211-3. doi: 10.1177/0310057X8000800222.
Two patients are described who had clinical anaphylaxis due to muscle relaxants. One patient had systemic hypersensitivity and positive intradermal tests to d-tubocurarine and alcuronium. The second had systemic hypersensitivity to d-tubocurarine and positive intradermal tests to d-tubocurarine, alcuronium, and pancuronium. It is suggested that positive intradermal tests to more than one relaxant may mean allergy to more than one relaxant rather than false positive test. Cross sensitivity between alcuronium and d-tubocurarine occurs and a similar situation may exist for suxamethonium and gallamine. When intradermal testing is carried out after anaesthetic reactions all relaxants should be tested.
本文描述了两名因肌肉松弛剂而发生临床过敏反应的患者。一名患者对d - 筒箭毒碱和阿库氯铵有全身超敏反应且皮内试验呈阳性。另一名患者对d - 筒箭毒碱有全身超敏反应，对d - 筒箭毒碱、阿库氯铵和泮库溴铵的皮内试验呈阳性。提示对一种以上松弛剂皮内试验呈阳性可能意味着对一种以上松弛剂过敏而非假阳性试验。阿库氯铵和d - 筒箭毒碱之间存在交叉敏感性，琥珀胆碱和加拉碘铵可能也存在类似情况。在麻醉反应后进行皮内试验时，应检测所有的松弛剂。
