Testa-Riva F, Puxeddu P
Anat Rec. 1980;196(4):363-72. doi: 10.1002/ar.1091960402.
Two secretory mechanisms (eccrine and apocrine) were observed by transmission and scanning electron microscopy in the same secretory cells of the human ceruminous glands. The eccrine secretion occurs as a typical exocytosis by fusion of the limiting membrane of the secretory granule with the apical plasmalemma. The apocrine secretion is more complex and takes place by sequential steps: bulging of the cellular apex into the lumen, constriction of the projection, and detachment of it from the cell. This mechanism generally causes the removal of the entire projection all at once by decapitation at its base; some variations of this process have been found, however, and are described in the present work. A double membrane, apparently separating the apical protrusion from the rest of the cell, is noticeable in our photographs. Nevertheless, even if this membrane is very similar to a demarcation layer, we consider it as an intercellular double membrane separating two obliquely sectioned cells.
通过透射电子显微镜和扫描电子显微镜，在人耵聍腺的同一分泌细胞中观察到两种分泌机制（外分泌和顶浆分泌）。外分泌以典型的胞吐作用形式发生，即分泌颗粒的限制膜与顶端质膜融合。顶浆分泌则更为复杂，通过一系列步骤进行：细胞顶端向管腔突出、突出部分收缩，然后从细胞上脱离。这种机制通常会导致突出部分在其基部被断头而一次性全部脱落；不过，已发现该过程存在一些变体，并在本研究中进行了描述。在我们的照片中，可以看到一层双膜，明显将顶端突出部分与细胞的其余部分分隔开。然而，即便这层膜与分界层非常相似，我们仍将其视为分隔两个斜切细胞的细胞间双膜。
