Richardson R W
Lancet. 1977 Dec 17;2(8051):1273-5. doi: 10.1016/s0140-6736(77)92674-5.
A comparison of the cost of laboratory-made reagents with that of commercial kits was made for three serum-enzyme estimations and three serum-hormone estimations. The cost of reagents in kit form could only be justified on economic grounds for serum aspartate transaminase, alanine transaminase, and lactic dehydrogenase if the laboratory performed less than about 35 tests per day. It is unlikely that the use of kits for serum tri-iodothyronine, thyroxine, and thyrotrophic hormone can be justified on economic grounds for any workload. It is estimated that between 2 million pounds and 3 million pounds is spent unnecessarily by the National Health Service each year to purchase commercially prepared reagents for the six tests studied.
对三种血清酶测定和三种血清激素测定的实验室自制试剂成本与市售试剂盒成本进行了比较。对于血清天冬氨酸转氨酶、丙氨酸转氨酶和乳酸脱氢酶，如果实验室每天进行的检测少于约35次，试剂盒形式的试剂成本在经济上才合理。对于任何工作量而言，基于经济理由使用试剂盒检测血清三碘甲状腺原氨酸、甲状腺素和促甲状腺激素不太可能是合理的。据估计，国家医疗服务体系每年不必要地花费200万至300万英镑来购买针对所研究的六项检测的商业制备试剂。
