Goette D K
Arch Dermatol. 1980 Jul;116(7):780-2.
Forty patients (39 white, one Oriental) had an isolated asymptomatic lichenoid keratotic lesion varying from bright red to violaceous to brown. The clinical diagnoses included basal cell carcinoma, actinic keratosis, Bowen's disease, and seborrheic keratosis. Histologically, lichenoid features prevailed, often indistinguishable from those of lichen planus. Although the majority of lesions occurred in sun-exposed skin and showed histologic evidence of solar elastosis, changes typical of carcinoma in situ were absent. The correct pathologic diagnosis of benign lichenoid keratosis was initially made in only seven cases.
40例患者(39例白人,1例东方人)有孤立的无症状苔藓样角化性损害,颜色从鲜红色到紫红色再到褐色不等。临床诊断包括基底细胞癌、光化性角化病、鲍温病和脂溢性角化病。组织学上,苔藓样特征占主导,常与扁平苔藓难以区分。尽管大多数损害发生在暴露于阳光的皮肤,并有日光性弹力组织变性的组织学证据,但原位癌的典型改变并不存在。最初只有7例被正确病理诊断为良性苔藓样角化病。