James W D, Odom R B
Arch Dermatol. 1980 Jul;116(7):807-11.
A case report of Dupuytren's contracture illustrates the functional and light and electron microscopic characteristics of the myofibroblast. The myofibroblast is now associated with an increasing number of diseases, and is believed to be a morphologic and functional variant of the fibroblast, which shows changes typical of smooth-muscle cells. Its presence may be suspected by light microscopy, but its ultrastructure is characteristic. Its distinctive electron microscopic features are a fibrillar system in the cytoplasm similar to that of a smooth muscle, nuclear deformations indicative of contraction, and surface membrane differentiations that provide attachment to neighboring cells and stroma.
一例杜普伊特伦挛缩症的病例报告阐明了肌成纤维细胞的功能以及光镜和电镜特征。如今，肌成纤维细胞与越来越多的疾病相关，并且被认为是成纤维细胞的一种形态和功能变体，它表现出平滑肌细胞的典型变化。通过光镜检查可能会怀疑其存在，但其超微结构具有特征性。其独特的电镜特征包括细胞质中类似于平滑肌的纤维系统、表明收缩的核变形以及提供与相邻细胞和基质附着的表面膜分化。
