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食管扩张术后菌血症:一项临床与实验研究。

Bacteremia after esophageal dilation: a clinical and experimental study.

作者信息

Golladay E S, Tepas J J, Pickard L R, Seibert J J, Brown R W, Haller J A

出版信息

Ann Thorac Surg. 1980 Jul;30(1):19-23. doi: 10.1016/s0003-4975(10)61196-4.

Abstract

Patients with esophageal stricture caused by caustic ingestion, reflux esophagitis, or esophageal anastomosis often require repeated dilation. These patients frequently have a short febrile course after dilation. After development of brain abscess following esophageal dilation in 1 patient, positive blood cultures were obtained in 4 patients immediately following esophageal dilation. Caustic strictures were produced in cats and esophageal dilations performed. Blood cultures were positive at one minute after dilation in 6 cats and at five minutes in 2 of those cats. The organism responsible in all clinical and three of four experimental examples was Staphylococcus aureus. It is suggested on the basis of this clinical and experimental data that patients undergoing esophageal dilation should have prophylactic coverage if they are immunosuppressed, if endocarditis prophylaxis is necessary, if they are infants, if they are diabetic, or if they had severe bacteremia following dilation.

摘要

因腐蚀性摄入、反流性食管炎或食管吻合术导致食管狭窄的患者常常需要反复扩张。这些患者在扩张后经常会有短暂的发热过程。1例患者在食管扩张后发生脑脓肿,另有4例患者在食管扩张后立即血培养呈阳性。在猫身上制造腐蚀性狭窄并进行食管扩张。6只猫在扩张后1分钟血培养呈阳性,其中2只猫在5分钟时血培养仍呈阳性。在所有临床病例以及4个实验病例中的3个病例中,致病微生物均为金黄色葡萄球菌。基于这些临床和实验数据表明,接受食管扩张的患者如果免疫功能低下、需要预防心内膜炎、是婴儿、患有糖尿病或者在扩张后发生严重菌血症,就应该进行预防性抗感染治疗。

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