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[慢性非特异性肺部疾病痰液的细胞学及某些细胞酶学特征]

[Cytologic and certain cytoenzymologic characteristics of sputum in chronic nonspecific lung diseases].

作者信息

Kazantseva V M

出版信息

Arkh Patol. 1980;42(4):63-8.

PMID:7396757
Abstract

The results of cytological examinations of sputum in 100 patients with chronic bronchitis in the period of exacerbration of the disease and in 70 patients with limited chronic inflammatory process in the lung clinically interpreted either as chronic pneumonia or pneumosclerosis are compared. Considerable accumulations of round-cell elements of inflammatory infiltrate with predominance of monocytes as well as predominant exfoliation of transitory bronchial epithelium and not ciliated epithelium were most frequently found in the group of patients with limited chronic inflammatory process in the lung. Fragments of atypical bronchial epithelium simulating cancer elements were found mostly in patients with chronic bronchitis showing marked an asthmatic component. In the course of exacerbation of chronic asthmatic bronchitis accompanied by positive clinical dynamics, there was an increase in the size of alveolar macrophages in the sputum and increase in the content of hydrolytic enzymes, acid phosphatase and nonspecific esterase, in them.

摘要

比较了100例慢性支气管炎患者在疾病加重期痰液的细胞学检查结果,以及70例临床上被解释为慢性肺炎或肺硬化的肺部局限性慢性炎症过程患者痰液的细胞学检查结果。在肺部局限性慢性炎症过程患者组中,最常发现炎症浸润的圆形细胞成分大量积聚,以单核细胞为主,以及过渡性支气管上皮而非纤毛上皮的大量脱落。模拟癌细胞成分的非典型支气管上皮碎片大多在有明显哮喘成分的慢性支气管炎患者中发现。在伴有阳性临床动态变化的慢性哮喘性支气管炎加重过程中,痰液中肺泡巨噬细胞的大小增加,其中水解酶、酸性磷酸酶和非特异性酯酶的含量增加。

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