[Role of neuromuscular connections in the morphogenetic process occurring in transplanted amphibian muscles].

Totally excized gastrocnemial muscles of the frog (Rana ridibunda) were replanted into their own matrix. The transplants were innervated by the tibial nerve which was specially brought to them or remained denervated. Reinnervation of the transplanted muscles started after 2 months, their contractility being recorded by the 4th month. At this time clear-cut differences in the weight and structure of innervated and denervated transplants related to secondary degeneration of regenerated muscle fibers were noted in the denervated transplants. Similar differences are recorded in the turtle and rat at earlier transplantation stages.