Byrd B F
Cancer. 1980 Aug 15;46(4 Suppl):1084-6. doi: 10.1002/1097-0142(19800815)46:4+<1084::aid-cncr2820461338>3.0.co;2-h.
The 28 Centers involved in the Breast Cancer Detection Demonstration Projects were initiated in 1973. The five-year commitment of some of the Projects will be completed during this calendar year, and those of others as late as 1981. The material available to us from the group of women studies is useful, but the accumulation of these data through the computer is still painfully slow. The last completed data available from the computer are those compiled through February 1979. They showed 273,108 women having completed their first examination, and the total number of examinations--1,011,709. In the breast biopsies that have been performed on patients from the study group, 85% have shown benign lesions, 14% have revealed invasive carcinoma, and 1% have shown preinvasive carcinoma, so-called carcinoma in situ. In general, these tumors have been at very early biological stages in the development of breast cancers. Some slightly less impressive figures have been obtained in those individuals who have discovered their cancers as a product of regular breast self-examination. The techniques of the survey clearly show that breast cancer can be picked up in a biologically earlier state and at a stage more amenable to definitive therapy.
参与乳腺癌检测示范项目的28个中心于1973年启动。部分项目的五年期承诺将在本历年完成，而其他项目的承诺则最晚到1981年。我们从女性研究群体中获得的资料很有用，但通过计算机积累这些数据的速度仍然极其缓慢。计算机提供的最新完整数据是截至1979年2月汇编的数据。数据显示，273,108名女性完成了首次检查，检查总数为1,011,709次。在对研究组患者进行的乳房活检中，85%显示为良性病变，14%为浸润性癌，1%为所谓的原位癌，即浸润前癌。总体而言，这些肿瘤在乳腺癌发展的生物学阶段都非常早期。在那些通过定期乳房自我检查发现癌症的个体中，得到的一些数据稍显逊色。调查技术清楚地表明，乳腺癌能够在生物学上更早的阶段被发现，且处于更适合确定性治疗的阶段。
